Get Drug Stereochemistry: Analytical Methods and Pharmacology, PDF

By Krzysztof Jozwiak,W. J. Lough,Irving W. Wainer

ISBN-10: 1420092383

ISBN-13: 9781420092387

Drug Stereochemistry: Analytical tools and Pharmacology, 3rd Edition covers all features of chiral medicinal drugs from educational, governmental, commercial, and scientific views, reflecting the various advances in ideas and method.

Topics include:

  • The use of enzymes within the synthesis and determination of enantiometrically natural compounds in drug discovery

  • How stereochemistry affects judgements made within the absorption, distribution, metabolism, excretion, and toxicity (ADMET) phases of drug discovery

  • Pharmacokinetics and pharmacodynamics and the problems confronted through the ultimate phases of the drug improvement process

  • The effect of the overseas convention on Harmonisation (ICH) at the use of unmarried isomer drugs

  • Chiral switches

  • The inspiration of molecular chiral attractiveness and the way it impacts the separation and behaviour of stereochemically natural drugs

  • Patent concerns surrounding chiral switches and the selling of unmarried enantiomer switches

The publication offers a high-quality heritage on stereochemistry, from its early heritage, together with an summary of phrases and ideas, to the present drug improvement technique, criminal and regulatory matters, and the recent stereoisomeric medicines. it's a one-stop reference for pharmaceutical scientists and chemists operating with chiral drug molecules.

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Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition (Drugs and the Pharmaceutical Sciences) by Krzysztof Jozwiak,W. J. Lough,Irving W. Wainer

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