Download e-book for iPad: Drug Design: Medicinal Chemistry: A Series of Monographs, by E. J. Ariëns

By E. J. Ariëns

ISBN-10: 0120603055

ISBN-13: 9780120603053

Drug layout, quantity V covers the basic methods to the advance of bioactive compounds. The e-book discusses the usage of operational schemes for analog synthesis in drug layout; the layout of enzyme inhibitors (transition country analogs); and the importance of structure-absorption-distribution relationships for drug layout.
The textual content describes the position of charge-transfer procedures within the motion of bioactive fabrics, in addition to the techniques to the rational blend of antimetabolites for melanoma chemotherapy. The physicochemical, quantum chemical, and different theoretical thoughts for the knowledge of the mechanism of motion of important frightened procedure (CNS) brokers, comparable to psychoactive medicinal drugs, narcotics, and narcotic antagonists and anesthetics, also are encompassed.
Chemists, biochemists, pharmacologists, and folks keen on drug layout will locate the booklet invaluable.

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Drug Design: Medicinal Chemistry: A Series of Monographs, Vol. 5 by E. J. Ariëns

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