Read e-book online Drug Design: Medicinal Chemistry: A Series of Monographs, PDF

By E. J. Ariëns

ISBN-10: 0120603020

ISBN-13: 9780120603022

Drug layout, quantity II covers the layout of bioactive compounds interacting with enzymes and enjoying a task in enzyme synthesis.
The publication discusses the modulation of pharmacokinetics through molecular manipulation; the standards within the layout of reversible and irreversible enzyme inhibitors; and the layout of organophosphate and carbamate inhibitors of cholinesterases. The textual content additionally describes the layout of reactivators for irreversibly blocked acetylcholinesterase; drug layout in keeping with the inhibition of protein synthesis within the context of weak enzymic reactions; in addition to the function of enzymes and their synthesis as a aim for antibiotic motion. The rational layout of antiviral brokers; the layout of penicillin; the layout of peptide hormone analogs; in addition to the advances within the layout of diuretics also are thought of. The ebook extra tackles the layout of biologically energetic steroids; the rational components within the improvement of better neuromuscular blockading brokers; and the layout of tumor-inhibitory alkylating medicinal drugs.
Pharmacologists, chemists, and folks serious about drug layout will locate the e-book invaluable.

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Drug Design: Medicinal Chemistry: A Series of Monographs, Vol. 2 by E. J. Ariëns


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