Cell Polarity and Subcellular RNA Localization (Results and - download pdf or read online

By Dietmar Richter

ISBN-10: 3540411429

ISBN-13: 9783540411420

ISBN-10: 3642074367

ISBN-13: 9783642074363

Selective cytoplasmic organelle and protein concentrating on has lengthy been proposal to represent the only determinant of mobile polarity and complexity. This view has been replaced, besides the fact that, by way of the invention of differential subcellular RNA distribution styles. during the last decade it has develop into transparent that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete mobile websites. during this ebook, a number of platforms are mentioned (e.g. Xenopus oocytes, mammalian mind, invertebrate frightened method) when it comes to RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational rules and the importance of the cytoskeleton for neuronal functionality and plasticity. It additionally discusses nucleocytoplasmic export of mRNA and viral RNA as one other instance of subcellular RNA kinesis.

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Cell Polarity and Subcellular RNA Localization (Results and Problems in Cell Differentiation) by Dietmar Richter

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