Biophysics of Computation: Information Processing in Single - download pdf or read online

By Christof Koch

ISBN-10: 0195104919

ISBN-13: 9780195104912

ISBN-10: 0195181999

ISBN-13: 9780195181999

Neural community learn usually builds at the fiction that neurons are easy linear threshold devices, thoroughly neglecting the hugely dynamic and intricate nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: details Processing in unmarried Neurons demanding situations this inspiration, utilizing richly specified experimental and theoretical findings from mobile biophysics to give an explanation for the repertoire of computational capabilities to be had to unmarried neurons. the writer indicates how person nerve cells can multiply, combine, or hold up synaptic inputs and the way info could be encoded within the voltage around the membrane, within the intracellular calcium focus, or within the timing of person spikes.
Key issues coated comprise the linear cable equation; cable thought as utilized to passive dendritic timber and dendritic spines; chemical and electric synapses and the way to regard them from a computational viewpoint; nonlinear interactions of synaptic enter in passive and energetic dendritic bushes; the Hodgkin-Huxley version of motion strength new release and propagation; section house research; linking stochastic ionic channels to membrane-dependent currents; calcium- and potassium-currents and their position in info processing; the function of diffusion, buffering and binding of calcium, and different messenger structures in details processing and garage; brief- and long term types of synaptic plasticity; simplified types of unmarried cells; stochastic features of neuronal firing; the character of the neuronal code; and unconventional types of sub-cellular computation.
Biophysics of Computation: info Processing in unmarried Neurons serves as a fantastic textual content for complicated undergraduate and graduate classes in mobile biophysics, computational neuroscience, and neural networks, and may attract scholars and pros in neuroscience, electric and desktop engineering, and physics.

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Biophysics of Computation: Information Processing in Single Neurons (Computational Neuroscience Series) by Christof Koch

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